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Influence of smoking and smoking cessation on levels of urinary 11-dehydro thromboxane B2.


ABSTRACT:

Background

Thromboxane is a key clinical risk endpoint of smoking-induced inflammation which has been associated in the pathogenesis of cardiovascular disease. The goal of this review is to quantify the effect of smoking and smoking cessation on one of its urinary metabolites, 11-dehydrothromboxaneB2.

Methods

PubMed and SCOPUS were searched to identify publications which report urinary 11-dehydrothromboxaneB2 levels in smokers and non-smokers, as well as articles reporting the effect of smoking cessation on urinary 11-dehydrothromboxaneB2 excretion.

Results

We found ten studies assessing urinary 11-dehydrothroboxaneB2 levels in smokers and non-smokers. Four papers reported the amount of urinary 11-dehydrothromboxaneB2</

SUBMITTER: van der Plas A 

PROVIDER: S-EPMC5977536 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature