Non-Coding RNA in the Pathogenesis, Progression and Treatment of Hypertension.

ABSTRACT: Hypertension is a complex, multifactorial disease that involves the coexistence of multiple risk factors, environmental factors and physiological systems. The complexities extend to the treatment and management of hypertension, which are still the pursuit of many researchers. In the last two decades, various genes have emerged as possible biomarkers and have become the target for investigations of specialized drug design based on its risk factors and the primary cause. Owing to the growing technology of microarrays and next-generation sequencing, the non-protein-coding RNAs (ncRNAs) have increasingly gained attention, and their status of redundancy has flipped to importance in normal cellular processes, as well as in disease progression. The ncRNA molecules make up a significant portion of

SUBMITTER: Leimena C 

PROVIDER: S-EPMC5979335 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature