Examining the Genetic Background of Porcine Muscle Growth and Development Based on Transcriptome and miRNAome Data.

ABSTRACT: Recently, selection in pigs has been focused on improving the lean meat content in carcasses; this focus has been most evident in breeds constituting a paternal component in breeding. Such sire-breeds are used to improve the meat quantity of cross-breed pig lines. However, even in one breed, a significant variation in the meatiness level can be observed. In the present study, the comprehensive analysis of genes and microRNA expression profiles in porcine muscle tissue was applied to identify the genetic background of meat content. The comparison was performed between whole gene expression and miRNA profiles of muscle tissue collected from two sire-line pig breeds (Pietrain, Hampshire). The RNA-seq approach allowed the identification of 627 and 416 differentially expressed genes (DEGs) betw

SUBMITTER: Ropka-Molik K 

PROVIDER: S-EPMC5979540 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature