Assessment of recording bias in pregnancy studies using health care databases: An application to neurologic conditions.

ABSTRACT:

Background

Pre-existing conditions are imperfectly recorded in health care databases. We assessed whether pre-existing neurologic conditions (epilepsy, multiple sclerosis [MS]) were differentially recorded in the presence of major obstetric outcomes (Caesarean delivery, preterm delivery, preeclampsia) in delivery records. We also evaluated the impact of differential recording on measures of frequency and association between the conditions and outcomes.

Methods

The 2011-2014 Truven Health MarketScan® Commercial Claims Dataset was used to identify pregnancies. We calculated the relative recording of epilepsy and MS at delivery hospitalization compared with a 270-day pre-delivery window both overall and by the presence of major obstetric outcomes. We estimated risk ratios for t

SUBMITTER: MacDonald SC 

PROVIDER: S-EPMC5980700 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature