CowPI: A Rumen Microbiome Focussed Version of the PICRUSt Functional Inference Software.

ABSTRACT: Metataxonomic 16S rDNA based studies are a commonplace and useful tool in the research of the microbiome, but they do not provide the full investigative power of metagenomics and metatranscriptomics for revealing the functional potential of microbial communities. However, the use of metagenomic and metatranscriptomic technologies is hindered by high costs and skills barrier necessary to generate and interpret the data. To address this, a tool for Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) was developed for inferring the functional potential of an observed microbiome profile, based on 16S data. This allows functional inferences to be made from metataxonomic 16S rDNA studies with little extra work or cost, but its accuracy relies on the availab

SUBMITTER: Wilkinson TJ 

PROVIDER: S-EPMC5981159 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature