Differentially Expressed Genes in Osteomyelitis Induced by Staphylococcus aureus Infection.

ABSTRACT: Osteomyelitis (OM) is a complicated and serious disease and its underlying molecular signatures of disease initiation and progression remain unclear. Staphylococcus aureus (S. aureus) is the most common causative agent of OM. Previous study of Banchereau et al. has established a link between whole blood transcription profiles and clinical manifestations in patients infected with S. aureus. However, the differentially expressed genes (DEGs) in OM induced by S. aureus infection have not been intensively investigated. In this study, we downloaded the gene expression profile dataset GSE30119 from Gene Expression Omnibus, and performed bioinformatic analysis to identify DEGs in S. aureus infection induced OM from the transcriptional level. The study consisted of 143

SUBMITTER: Chen P 

PROVIDER: S-EPMC5982613 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature