The Role of Peroxisome Proliferator-Activated Receptors and Their Transcriptional Coactivators Gene Variations in Human Trainability: A Systematic Review.

ABSTRACT:

Background

The peroxisome proliferator-activated receptors (PPARA, PPARG, PPARD) and their transcriptional coactivators' (PPARGC1A, PPARGC1B) gene polymorphisms have been associated with muscle morphology, oxygen uptake, power output and endurance performance. The purpose of this review is to determine whether the PPARs and/or their coactivators' polymorphisms can predict the training response to specific training stimuli.

Methods

In accordance with the Preferred Reporting Items for Systematic Reviews and Meta Analyses, a literature review has been run for a combination of PPARs and physical activity key words.

Results

All ten of the included studies were performed using aerobic training in general, sedentary or elderly populations f

SUBMITTER: Petr M 

PROVIDER: S-EPMC5983571 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature