Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults.

ABSTRACT:

Background

Current prevention guidelines recommend using the Pooled Cohort Equation (PCE) for 10-year atherosclerotic cardiovascular disease (CVD) risk assessment. However, the PCE has serious limitations in older adults: it excludes heart failure (HF) hospitalization, estimates 10-year risk, which may not be the most relevant time frame, and is not indicated for individuals age >79 years.

Objectives

This study sought to determine whether adding biomarkers to PCE variables improves global CVD (coronary heart disease, stroke, and HF) risk prediction in older adults over a shorter time period.

Methods

Atherosclerosis Risk in Communities study participants without prevalent CVD including HF (n = 4,760; age 75.4 ± 5.1 years) were followed for incident global CVD events. A

SUBMITTER: Saeed A 

PROVIDER: S-EPMC5984171 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature