Corticoinsular circuits encode subjective value expectation and violation for effortful goal-directed behavior.

ABSTRACT: We are presented with choices each day about how to invest our effort to achieve our goals. Critically, these decisions must frequently be made under conditions of incomplete information, where either the effort required or possible reward to be gained is uncertain. Such choices therefore require the development of potential value estimates to guide effortful goal-directed behavior. To date, however, the neural mechanisms for this expectation process are unknown. Here, we used computational fMRI during an effort-based decision-making task where trial-wise information about effort costs and reward magnitudes was presented separately over time, thereby allowing us to model distinct effort/reward computations as choice-relevant information unfolded. We found that ventromedial prefrontal corte

SUBMITTER: Arulpragasam AR 

PROVIDER: S-EPMC5984520 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature