Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis.

ABSTRACT: The chromium photocatalyzed cyclopropanation of diazo reagents with electron-rich alkenes is described. The transformation occurs under mild conditions and features specific distinctions from traditional diazo-based cyclopropanations (e.g., avoiding β-hydride elimination, chemoselectivity considerations, etc.). The reaction appears to work most effectively using chromium catalysis, and a number of decorated cyclopropanes can be accessed in generally good yields.

SUBMITTER: Sarabia FJ 

PROVIDER: S-EPMC5985524 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature