Whole-genome sequencing and antimicrobial resistance in Brucella melitensis from a Norwegian perspective.

ABSTRACT: Brucellosis is a rarely encountered infection in Norway. The aim of this study was to explore all Brucella melitensis isolates collected in Norway from 1999 to 2016 in relation to origin of infection and antimicrobial resistance patterns. A total of 23 isolates were analysed by whole-genome sequencing and compared with selected sequences of B. melitensis available from NCBI. Additionally, SNP analysis in antibiotic resistance determining genes was performed. The majority belonged to the East Mediterranean clade (genotype II), while the remaining isolates belonged to the African clade (genotype III). These results indicate that human brucellosis in Norway is related to travels or migration from the Middle East, Asia or Africa, in accordance with results from Germany, Denmark and Sweden. Ant

SUBMITTER: Johansen TB 

PROVIDER: S-EPMC5986768 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature