Analysis of Anatomic and Functional Measures in X-Linked Retinoschisis.

ABSTRACT:

Purpose

To examine the symmetry of structural and functional parameters between eyes in patients with X-linked retinoschisis (XLRS), as well as changes in visual acuity and electrophysiology over time.

Methods

This is a single-center observational study of 120 males with XLRS who were evaluated at the National Eye Institute. Examinations included best-corrected visual acuity for all participants, as well as ERG recording and optical coherence tomography (OCT) on a subset of participants. Statistical analyses were performed using nonparametric Spearman correlations and linear regression.

Results

Our analyses demonstrated a statistically significant correlation of structural and functional measures between the two eyes of XLRS patients for all parameters. OCT central ma

SUBMITTER: Cukras CA 

PROVIDER: S-EPMC5987578 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature