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Impact of gender and genetics on emotion processing in Parkinson's disease - A multimodal study.


ABSTRACT: •Understanding of the phenotypic heterogeneity of Parkinson's disease is needed.•Gender and genetics determine manifestation and progression of Parkinson's disease.•Altered emotion processing in Parkinson's disease is specific to male patients.•This is influenced by endocrinal and genetic factors in both genders.•This finding may impact the diagnosis and treatment of emerging clinical features.

SUBMITTER: Heller J 

PROVIDER: S-EPMC5987844 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Impact of gender and genetics on emotion processing in Parkinson's disease - A multimodal study.

Heller Julia J   Mirzazade Shahram S   Romanzetti Sandro S   Habel Ute U   Derntl Birgit B   Freitag Nils M NM   Schulz Jörg B JB   Dogan Imis I   Reetz Kathrin K  

NeuroImage. Clinical 20180131


•Understanding of the phenotypic heterogeneity of Parkinson's disease is needed.•Gender and genetics determine manifestation and progression of Parkinson's disease.•Altered emotion processing in Parkinson's disease is specific to male patients.•This is influenced by endocrinal and genetic factors in both genders.•This finding may impact the diagnosis and treatment of emerging clinical features. ...[more]

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