¹⁸F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus.

ABSTRACT:

Background

Idiopathic normal pressure hydrocephalus (iNPH) is an important and treatable cause of neurologic impairment. Diagnosis is complicated due to symptoms overlapping with other age related disorders. The pathophysiology underlying iNPH is not well understood. We explored FDG-PET abnormalities in iNPH patients in order to determine if FDG-PET may serve as a biomarker to differentiate iNPH from common neurodegenerative disorders.

Methods

We retrospectively compared ¹⁸F-FDG PET-CT imaging patterns from seven iNPH patients (mean age 74 ± 6 years) to age and sex matched controls, as well as patients diagnosed with clinical Alzheimer's disease dementia (AD), Dementia with Lewy Bodies (DLB) and Parkinson's Disease Dementia (PDD), and behavioral variant frontotemp

SUBMITTER: Townley RA 

PROVIDER: S-EPMC5987871 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature