Health economic evaluation of a serum-based blood test for brain tumour diagnosis: exploration of two clinical scenarios.

ABSTRACT: OBJECTIVES:To determine the potential costs and health benefits of a serum-based spectroscopic triage tool for brain tumours, which could be developed to reduce diagnostic delays in the current clinical pathway. DESIGN:A model-based health pre-trial economic assessment. Decision tree models were constructed based on simplified diagnostic pathways. Models were populated with parameters identified from rapid reviews of the literature and clinical expert opinion. SETTING:Explored as a test in both primary and secondary care (neuroimaging) in the UK health service, as well as application to the USA. PARTICIPANTS:Calculations based on an initial cohort of 10 000 patients. In primary care, it is estimated that the volume of tests would approach 75 000 per annum. The volume of tests in secondary

SUBMITTER: Gray E 

PROVIDER: S-EPMC5988134 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature