Data on haplotype diversity in the hypervariable region I, II and III of mtDNA amongst the Brahmin population of Haryana.

ABSTRACT: Human mitochondrial DNA (mtDNA) is routinely analysed for pathogenic mutations, evolutionary studies, estimation of time of divergence within or between species, phylogenetic studies and identification of degraded remains. The data on various regions of human mtDNA has added enormously to the knowledge pool of population genetics as well as forensic genetics. The displacement-loop (D-loop) in the control region of mtDNA is rated as the most rapidly evolving part, due to the presence of variations in this region. The control region consists of three hypervariable regions. These hypervariable regions (HVI, HVII and HVIII) tend to mutate 5-10 times faster than nuclear DNA. The high mutation rate of these hypervariable regions is used in population genetic studies and human identity testing. I

SUBMITTER: Verma K 

PROVIDER: S-EPMC5988218 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature