Seasonal influenza vaccine effectiveness against laboratory-confirmed influenza hospitalizations - Latin America, 2013.

ABSTRACT:

Background

Despite widespread utilization of influenza vaccines, effectiveness (VE) has not been routinely measured in Latin America.

Methods

We used a case test-negative control design to estimate trivalent inactivated influenza VE against laboratory-confirmed influenza among hospitalized children aged 6months-5years and adults aged ≥60years which are age-groups targeted for vaccination. We sought persons with severe acute respiratory infections (SARI), hospitalized at 71 sentinel hospitals in Argentina, Brazil, Chile, Colombia, Costa Rica, El Salvador, Honduras, Panama, and Paraguay during January-December 2013. Cases had an influenza virus infection confirmed by real-time reverse transcription PCR (rRT-PCR); controls had a negative rRT-PCR result for influenza viruses. We

SUBMITTER: El Omeiri N 

PROVIDER: S-EPMC5988548 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature