Three-Dimensional Representation of Motor Space in the Mouse Superior Colliculus.

ABSTRACT: From the act of exploring an environment to that of grasping a cup of tea, animals must put in register their motor acts with their surrounding space. In the motor domain, this is likely to be defined by a register of three-dimensional (3D) displacement vectors, whose recruitment allows motion in the direction of a target. One such spatially targeted action is seen in the head reorientation behavior of mice, yet the neural mechanisms underlying these 3D behaviors remain unknown. Here, by developing a head-mounted inertial sensor for studying 3D head rotations and combining it with electrophysiological recordings, we show that neurons in the mouse superior colliculus are either individually or conjunctively tuned to the three Eulerian components of head rotation. The average displacement ve

SUBMITTER: Wilson JJ 

PROVIDER: S-EPMC5988568 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature