Irritable bowel syndrome in children: Current knowledge, challenges and opportunities.

ABSTRACT: Irritable bowel syndrome (IBS) is a common and troublesome disorder in children with an increasing prevalence noted during the past two decades. It has a significant effect on the lives of affected children and their families and poses a significant burden on healthcare systems. Standard symptom-based criteria for diagnosis of pediatric IBS have changed several times during the past two decades and there are some differences in interpreting symptoms between different cultures. This has posed a problem when using them to diagnose IBS in clinical practice. A number of potential patho-physiological mechanisms have been described, but so far the exact underlying etiology of IBS is unclear. A few potential therapeutic modalities have been tested in children and only a small number of them have

SUBMITTER: Devanarayana NM 

PROVIDER: S-EPMC5989237 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature