Ontology highlight
ABSTRACT:
SUBMITTER: Zhang YL
PROVIDER: S-EPMC5989280 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Journal of immunology research 20180524
Integrin subunit alpha 9 (ITGA9) mediates cell-cell and cell-matrix adhesion, cell migration, and invasion through binding different kinds of extracellular matrix (ECM) components. However, its potential role and underlying molecular mechanisms remain unclear in hepatocellular carcinoma (HCC). Here, we found that ITGA9 expression was obviously decreased in patients with HCC, which was negatively correlated with HCC growth and metastasis. ITGA9 overexpression significantly inhibited cell prolifer ...[more]