Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.

ABSTRACT: An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(ii) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN(3))(2+) complex.

SUBMITTER: Tseng TS 

PROVIDER: S-EPMC5989323 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature