Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages.

ABSTRACT: Based on complete bacterial genome sequence data, we demonstrate a correlation between bacterial chromosome length and the G+C content of the genome, with longer genomes having higher G+C contents. The correlation value decreases at shorter genome sizes, where there is a wider spread of G+C values. However, although significant (P<0.001), the correlation value (Pearson R=0.58) suggests that other factors also have a significant influence. A similar pattern was seen for plasmids; longer plasmids had higher G+C values, although the large number of shorter plasmids had a wide spread of G+C values. There was also a significant (P<0.0001) correlation between the G+C content of plasmids and the G+C content of their bacterial host. Conversely, the G+C content of bacteriophages tended to reduce wi

SUBMITTER: Almpanis A 

PROVIDER: S-EPMC5989581 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature