Variation in antibiotic use among and within different settings: a systematic review.

ABSTRACT:

Objectives

Variation in antibiotic use may reflect inappropriate use. We aimed to systematically describe the variation in measures for antibiotic use among settings or providers. This study was conducted as part of the innovative medicines initiative (IMI)-funded international project DRIVE-AB.

Methods

We searched for studies published in MEDLINE from January 2004 to January 2015 reporting variation in measures for systemic antibiotic use (e.g. DDDs) in inpatient and outpatient settings. The ratio between a study's reported maximum and minimum values of a given measure [maximum:minimum ratio (MMR)] was calculated as a measure of variation. Similar measures were grouped into categories and when possible the overall median ratio and IQR were calculated.

Results

One hun

SUBMITTER: Zanichelli V 

PROVIDER: S-EPMC5989604 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature