Multi-resolution simulation of focused ultrasound propagation through ovine skull from a single-element transducer.

ABSTRACT: Transcranial focused ultrasound (tFUS) is emerging as a non-invasive brain stimulation modality. Complicated interactions between acoustic pressure waves and osseous tissue introduce many challenges in the accurate targeting of an acoustic focus through the cranium. Image-guidance accompanied by a numerical simulation is desired to predict the intracranial acoustic propagation through the skull; however, such simulations typically demand heavy computation, which warrants an expedited processing method to provide on-site feedback for the user in guiding the acoustic focus to a particular brain region. In this paper, we present a multi-resolution simulation method based on the finite-difference time-domain formulation to model the transcranial propagation of acoustic waves from a single-elem

SUBMITTER: Yoon K 

PROVIDER: S-EPMC5990022 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature