Treatment of Oligometastatic Hormone-Sensitive Prostate Cancer: A Comprehensive Review.

ABSTRACT: With advancements in diagnostic techniques, including molecular and clinical imaging, that directly target cancer cells, oligometastatic prostate cancer (PCa) is being diagnosed in patients who were, in the past, considered to have localized disease. With accumulating evidence, there has been a paradigm shift in considering aggressive treatments targeted at both the primary tumor and metastatic lesions in an aim to avoid and delay the need for palliative treatments and, ultimately, to achieve survival benefits. However, many questions still remain unanswered regarding the understanding of oligometastatic PCa, from its definition to optimal treatment strategies for each individual. Limited retrospective studies have suggested that interventions, including local and/or metastasis-directed th

SUBMITTER: Koo KC 

PROVIDER: S-EPMC5990677 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature