Copper-catalysed regioselective sulfenylation of indoles with sodium sulfinates.

ABSTRACT: A copper-catalysed sulfenylation of indoles with sodium sulfinates that affords 3-sulfenylindoles in good-to-excellent yields in N,N-dimethyl formamide (DMF) is described. In the process, DMF serves not only as a solvent but also as a reductant. This transformation is easy to carry out and has mild reaction conditions and good functional group tolerance.

SUBMITTER: Luo X 

PROVIDER: S-EPMC5990840 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature