Impact of contraceptive initiation on vaginal microbiota.

ABSTRACT:

Background

Data evaluating the impact of contraceptives on the vaginal microbiome are limited and inconsistent.

Objective

We hypothesized that women initiating copper intrauterine device use would have increased bacterial vaginosis and bacterial vaginosis-associated microbes with use compared to women initiating and using hormonal contraceptive methods.

Study design

Vaginal swabs (N = 1047 from 266 participants seeking contraception) for Nugent score determination of bacterial vaginosis and quantitative polymerase chain reaction analyses for assessment of specific microbiota were collected from asymptomatic, healthy women aged 18-35 years in Harare, Zimbabwe, who were confirmed to be free of nonstudy hormones by mass spectrometry at each visit. Contraception was initi

SUBMITTER: Achilles SL 

PROVIDER: S-EPMC5990849 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature