Walnut Consumption Alters the Gastrointestinal Microbiota, Microbially Derived Secondary Bile Acids, and Health Markers in Healthy Adults: A Randomized Controlled Trial.

ABSTRACT:

Background

Epidemiologic data suggest that diets rich in nuts have beneficial health effects, including reducing total and cause-specific mortality from cancer and heart disease. Although there is accumulating preclinical evidence that walnuts beneficially affect the gastrointestinal microbiota and gut and metabolic health, these relations have not been investigated in humans.

Objective

We aimed to assess the impact of walnut consumption on the human gastrointestinal microbiota and metabolic markers of health.

Methods

A controlled-feeding, randomized crossover study was undertaken in healthy men and women [n = 18; mean age = 53.1 y; body mass index (kg/m2): 28.8]. Study participants received isocaloric diets containing 0 or 42 g walnuts/d for two 3-wk periods, with a

SUBMITTER: Holscher HD 

PROVIDER: S-EPMC5991202 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature