Coordinated regulation of core and accessory genes in the multipartite genome of Sinorhizobium fredii.

ABSTRACT: Prokaryotes benefit from having accessory genes, but it is unclear how accessory genes can be linked with the core regulatory network when developing adaptations to new niches. Here we determined hierarchical core/accessory subsets in the multipartite pangenome (composed of genes from the chromosome, chromid and plasmids) of the soybean microsymbiont Sinorhizobium fredii by comparing twelve Sinorhizobium genomes. Transcriptomes of two S. fredii strains at mid-log and stationary growth phases and in symbiotic conditions were obtained. The average level of gene expression, variation of expression between different conditions, and gene connectivity within the co-expression network were positively correlated with the gene conservation level from strain-specific accessory genes to genus core. C

SUBMITTER: Jiao J 

PROVIDER: S-EPMC5991415 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature