Serum magnesium, phosphorus, and calcium levels and subclinical calcific aortic valve disease: A population-based study.

ABSTRACT: BACKGROUND AND AIMS:Calcific aortic valve disease (CAVD) is the most common valve disease. Although micronutrients are known to contribute to cardiovascular disease, the relationship with CAVD remains poorly evaluated. We examined the association of serum levels of magnesium, phosphorus, and calcium with prevalence, incidence, and progression of aortic valve calcification (AVC). METHODS:We conducted a prospective study in a population-based sample of Japanese men aged 40-79 years without known cardiovascular disease and chronic kidney disease at baseline, and quantified AVC from serial computed tomographic images with the Agatston method. RESULTS:Of 938 participants at baseline (mean age, 63.7 ± 9.9 years), AVC prevalence was observed in 173 (18.4%). Of 596 participants without baseline AV

SUBMITTER: Hisamatsu T 

PROVIDER: S-EPMC5991478 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature