Sensor-based gait analysis in atypical parkinsonian disorders.

ABSTRACT:

Background and objectives

Gait impairment and reduced mobility are typical features of idiopathic Parkinson's disease (iPD) and atypical parkinsonian disorders (APD). Quantitative gait assessment may have value in the diagnostic workup of parkinsonian patients and as endpoint in clinical trials. The study aimed to identify quantitative gait parameter differences in iPD and APD patients using sensor-based gait analysis and to correlate gait parameters with clinical rating scales.

Subjects and methods

Patients with iPD and APD including Parkinson variant multiple system atrophy and progressive supranuclear palsy matched for age, gender, and Hoehn and Yahr (≤3) were recruited at two Movement Disorder Units and assessed using standardized clinical rating scales (MDS-UPDRS-3, UMS

SUBMITTER: Raccagni C 

PROVIDER: S-EPMC5991583 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature