Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study.

ABSTRACT:

Background

The widespread use of wireless devices during the last decades is raising concerns about adverse health effects of the radiofrequency electromagnetic radiation (RF-EMR) emitted from these devices. Recent research is focusing on unraveling the underlying mechanisms of RF-EMR and potential cellular targets. The "omics" high-throughput approaches are powerful tools to investigate the global effects of RF-EMR on cellular physiology.

Methods

In this work, C57BL/6 adult male mice were whole-body exposed (n_Exp  = 8) for 2 hr to GSM 1800 MHz mobile phone radiation at an average electric field intensity range of 4.3-17.5 V/m or sham-exposed (n_SE  = 8), and the RF-EMR effects on the hippocampal lipidome and transcriptome profiles were assess

SUBMITTER: Fragopoulou AF 

PROVIDER: S-EPMC5991598 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature