Genetic influences on prefrontal activation during a verbal fluency task in children: A twin study using near-infrared spectroscopy.

ABSTRACT:

Objective

The genetic and environmental influences on prefrontal function in childhood are underinvestigated due to the difficulty of measuring prefrontal function in young subjects, for which near-infrared spectroscopy (NIRS) is a suitable functional neuroimaging technique that facilitates the easy and noninvasive measurement of blood oxygenation in the superficial cerebral cortices.

Method

Using a two-channel NIRS arrangement, we measured changes in bilateral prefrontal blood oxygenation during a category version of the verbal fluency task (VFT) in 27 monozygotic twin pairs and 12 same-sex dizygotic twin pairs ages 5-17 years. We also assessed the participant's full-scale intelligence quotient (FIQ) and retrieved parental socioeconomic status (SES). Classical structured eq

SUBMITTER: Sakakibara E 

PROVIDER: S-EPMC5991600 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature