Medicare part D prescribing for direct oral anticoagulants in the United States: Cost, use and the "rubber effect".

ABSTRACT:

Introduction

Direct oral anticoagulants (DOAC) have gained an increased share over warfarin for prevention and treatment of thromboembolic disease. We studied DOAC adoption across providers and medical specialties.

Methods

Retrospective, cross-sectional analysis of Medicare Part D public use files (PUF), 2013 to 2015. We summarized prescription data for claims and drug payment, stratified by drug class, specialty and calendar year. We treated DOAC claims as a count outcome and explored patterns of expansion across prescribers via a truncated negative binomial regression. We described dispersion and spread in DOAC prescribing, across hospital referral regions (HRRs), including the p90/p10 ratios, and the median absolute deviation from the median.

Results

In 2015 part D

SUBMITTER: Ziakas PD 

PROVIDER: S-EPMC5991647 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature