The effectiveness of transarterial chemoembolization in recurrent hepatocellular-cholangiocarcinoma after resection.

ABSTRACT:

Background

Combined hepatocellular-cholangiocarcinoma (cHCC-CC) can present as a hypervascular or peripherally enhancing tumor in dynamic imaging. We evaluated the effect of transarterial chemoembolization (TACE) on prognosis according to post-operative recurrence imaging patterns.

Methods

We retrospectively analyzed 42 cHCC-CC and 59 hepatocellular carcinoma (HCC-control) patients at the Asan Medical Center. We classified recurrent cHCC-CC according to enhancement pattern (globally enhancing: GE cHCC-CC, peripherally enhancing: PE cHCC-CC) and evaluated tumor response, time-to-local progression (TTPlocal), and overall survival (OS).

Results

The GE cHCC-CC group had a significantly higher best objective response rate (complete remission + partial response) than the PE

SUBMITTER: Na SK 

PROVIDER: S-EPMC5991684 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature