Geographic disparity in kidney transplantation under KAS.

ABSTRACT: The Kidney Allocation System fundamentally altered kidney allocation, causing a substantial increase in regional and national sharing that we hypothesized might impact geographic disparities. We measured geographic disparity in deceased donor kidney transplant (DDKT) rate under KAS (6/1/2015-12/1/2016), and compared that with pre-KAS (6/1/2013-12/3/2014). We modeled DSA-level DDKT rates with multilevel Poisson regression, adjusting for allocation factors under KAS. Using the model we calculated a novel, improved metric of geographic disparity: the median incidence rate ratio (MIRR) of transplant rate, a measure of DSA-level variation that accounts for patient casemix and is robust to outlier values. Under KAS, MIRR was _1.75 1.81_1.86 for adults, meaning that similar ca

SUBMITTER: Zhou S 

PROVIDER: S-EPMC5992006 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature