Impact of the posttransplant lymphoproliferative disorder subtype on survival.

ABSTRACT:

Background

Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the impact of the PTLD histologic subtype on survival in a large data set.

Methods

Case series were identified on PubMed with the search terms post-transplant lymphoproliferative disorder/disease, PTLD, and solid organ transplantation, with additional publications identified through reference lists. The patient characteristics, immunosuppressive regimen, treatment, survival, and follow-up time for 306 cases were extracted from 94 articles, and these cases were com

SUBMITTER: Koff JL 

PROVIDER: S-EPMC5992039 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature