Volume of interest delineation techniques for ¹⁸F-FDG PET-CT scans during neoadjuvant extremity soft tissue sarcoma treatment in adults: a feasibility study.

ABSTRACT:

Background

This study explores various volume of interest (VOI) delineation techniques for fluorine-18-fluorodeoxyglucose positron emission tomography with computed tomography (¹⁸F-FDG PET-CT) scans during neoadjuvant extremity soft tissue sarcoma (ESTS) treatment.

Results

During neoadjuvant treatment, hyperthermic isolated limb perfusion (HILP) and preoperative external beam radiotherapy (EBRT), 11 patients underwent three ¹⁸F-FDG PET-CT scans. The first scan was made prior to the HILP, the second after the HILP but prior to the start of the EBRT, and the third prior to surgical resection. An automatically drawn VOI_auto, a manually drawn VOI_man, and two gradient-based semi-automatically drawn VOIs (VOI_grad and VOI_g

SUBMITTER: Stevenson MG 

PROVIDER: S-EPMC5992109 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature