Novel computer-based testing shows multi-domain cognitive dysfunction in patients with multiple sclerosis.

ABSTRACT:

Background

Although cognitive dysfunction is a leading cause of disability and poor quality of life in patients with multiple sclerosis (MS), it is infrequently tested in routine clinical evaluation. Development of a cognitive testing paradigm that captured MS-related cognitive dysfunction and could be obtained in a routine clinical setting may increase surveillance and recognition of cognitive dysfunction.

Objectives

This was a pilot study to determine if Cognivue could find cognitive performance differences between patients with MS and healthy controls (HC).Methods: A total of 24 patients with MS and 12 HCs between 18 and 50 years old were enrolled. Baseline testing included an Expanded Disability Scale (EDSS), paced auditory serial additions test (PASAT), sy

SUBMITTER: Smith AD 

PROVIDER: S-EPMC5993067 | biostudies-literature | 2018 Apr-Jun

REPOSITORIES: biostudies-literature