Wider perioperative glycemic fluctuations increase risk of postoperative atrial fibrillation and ICU length of stay.

ABSTRACT:

Introduction

Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery associated with increased morbidity and mortality. Although sustained hyperglycemia is a known risk factor of AF and poor ICU outcomes, emerging in-vitro studies reveal acute glycemic fluctuations to be an additional independent predictor of AF. The effect of acute glycemic fluctuations on the incidence of POAF in the clinical setting remains unclear. We aim to investigate the effect of the magnitude of acute perioperative glycemic fluctuations on the incidence of POAF in a multi-ethnic Southeast-Asian population.

Methods

We obtained data from1743 patients who underwent elective CABG in a tertiary heart centre from 2009-2011. Patients were kept to a tight baseline glycemi

SUBMITTER: Sim MA 

PROVIDER: S-EPMC5993260 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature