Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches.

ABSTRACT:

Purpose of review

The aim of this article is to discuss how allergen-specific immunotherapy (AIT) can be improved through molecular approaches. We provide a summary of next-generation molecular AIT approaches and of their clinical evaluation. Furthermore, we discuss the potential of next generation molecular AIT forms for the treatment of severe manifestations of allergy and mention possible future molecular strategies for the secondary and primary prevention of allergy.

Recent findings

AIT has important advantages over symptomatic forms of allergy treatment but its further development is limited by the quality of the therapeutic antigen preparations which are derived from natural allergen sources. The field of allergy diagnosis is currently undergoing a dramatic improvement

SUBMITTER: Curin M 

PROVIDER: S-EPMC5994214 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature