Peripheral Pigmented Retinal Lesions in Stargardt Disease.

ABSTRACT:

Purpose

To investigate the prevalence of peripheral pigmented retinal lesions and associated clinical findings in patients with Stargardt disease.

Design

Retrospective case series.

Methods

Records at a single academic institution were reviewed for patients with genetically confirmed Stargardt disease with peripheral pigmented retinal lesions on wide-field retinal imaging. For this cohort we described demographics, clinical features, and pathogenic variants.

Results

Out of 62 patients with Stargardt disease and wide-field retinal imaging, 14 had peripheral pigmented retinal lesions. These flat, subretinal lesions were located in the mid or far periphery and had well-defined borders, resembling congenital hypertrophy of retinal pigment epithelium (CHRPE) lesions.

SUBMITTER: Zhao PY 

PROVIDER: S-EPMC5994923 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature