Ontology highlight
ABSTRACT:
SUBMITTER: Ishidate T
PROVIDER: S-EPMC5994929 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Molecular cell 20180501 4
Animal cells have a remarkable capacity to adopt durable and heritable gene expression programs or epigenetic states that define the physical properties and diversity of somatic cell types. The maintenance of epigenetic programs depends on poorly understood pathways that prevent gain or loss of inherited signals. In the germline, epigenetic factors are enriched in liquid-like perinuclear condensates called nuage. Here, we identify the deeply conserved helicase-domain protein, ZNFX-1, as an epige ...[more]