Choosy Wolves? Heterozygote Advantage But No Evidence of MHC-Based Disassortative Mating.

ABSTRACT: A variety of nonrandom mate choice strategies, including disassortative mating, are used by vertebrate species to avoid inbreeding, maintain heterozygosity and increase fitness. Disassortative mating may be mediated by the major histocompatibility complex (MHC), an important gene cluster controlling immune responses to pathogens. We investigated the patterns of mate choice in 26 wild-living breeding pairs of gray wolf (Canis lupus) that were identified through noninvasive genetic methods and genotyped at 3 MHC class II and 12 autosomal microsatellite (STR) loci. We tested for deviations from random mating and evaluated the covariance of genetic variables at functional and STR markers with fitness proxies deduced from pedigree reconstructions. Results did not show evidences of MHC-based dis

SUBMITTER: Galaverni M 

PROVIDER: S-EPMC5994966 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature