Hybrid Magnetic Resonance Imaging and Positron Emission Tomography With Fluorodeoxyglucose to Diagnose Active Cardiac Sarcoidosis.

ABSTRACT:

Objectives

The purpose of this study was to explore the diagnostic usefulness of hybrid cardiac magnetic resonance (CMR) and positron emission tomography (PET) using ¹⁸F-fluorodeoxyglucose (FDG) for active cardiac sarcoidosis.

Background

Active cardiac sarcoidosis (aCS) is underdiagnosed and has a high mortality.

Methods

Patients with clinical suspicion of aCS underwent hybrid CMR/PET with late gadolinium enhancement (LGE) and FDG to assess the pattern of injury and disease activity, respectively. Patients were categorized visually as magnetic resonance (MR)+PET+ (characteristic LGE aligning exactly with increased FDG uptake), MR+PET- (characteristic LGE but no increased FDG), MR-PET- (neither characteristic LGE nor increased FDG), and MR-PET+ (increased FD

SUBMITTER: Dweck MR 

PROVIDER: S-EPMC5995315 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature