A Supervised Exercise Intervention for Youth at Risk for Psychosis: An Open-Label Pilot Study.

ABSTRACT:

Objective

A rapidly accumulating body of research suggests that exercise can improve symptoms and well-being in patients suffering from psychosis. Exercise may also promote neurogenesis in the hippocampus, a structure that plays an important role in the pathophysiology of psychosis. To date, there has not been an intervention focused on exercise prior to the onset of psychosis, a critical time for prevention of more serious illness.

Methods

In this pilot study, 12 young adults at ultrahigh risk (UHR) for psychosis were enrolled in a 12-week open-label exercise intervention. Participants were randomly assigned to exercise 2 or 3 times each week and exercised between 65% and 85% of maximum oxygen capacity (Vo2max) for 30 minutes each session under the supervision of an exercis

SUBMITTER: Dean DJ 

PROVIDER: S-EPMC5995728 | biostudies-literature | 2017 Nov-Dec

REPOSITORIES: biostudies-literature