Developing and Refining New Candidate Criteria for Systemic Lupus Erythematosus Classification: An International Collaboration.

ABSTRACT:

Objective

To define candidate criteria within multiphase development of systemic lupus erythematosus (SLE) classification criteria, jointly supported by the American College of Rheumatology and the European League Against Rheumatism. Prior steps included item generation and reduction by Delphi exercise, further narrowed to 21 items in a nominal group technique exercise. Our objectives were to apply an evidence-based approach to the 21 candidate criteria, and to develop hierarchical organization of criteria within domains.

Methods

A literature review identified the sensitivity and specificity of the 21 candidate criteria. Data on the performance of antinuclear antibody (ANA) as an entry criterion and operating characteristics of the candidate criteria in early SLE patients we

SUBMITTER: Tedeschi SK 

PROVIDER: S-EPMC5996759 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature