Peptidomics dataset: Blood plasma and serum samples of healthy donors fractionated on a set of chromatography sorbents.

ABSTRACT: Blood as connective tissue potentially contains evidence of all processes occurring within the organism, at least in trace amounts (Petricoin et al., 2006) [1]. Because of their small size, peptides penetrate cell membranes and epithelial barriers more freely than proteins. Among the peptides found in blood, there are both fragments of proteins secreted by various tissues and performing their function in plasma and receptor ligands: hormones, cytokines and mediators of cellular response (Anderson et al., 2002) [2]. In addition, in minor amounts, there are peptide disease markers (for example, oncomarkers) and even foreign peptides related to pathogenic organisms and infection agents. To propose an approach for detailed peptidome characterization, we carried out an LC-MS/MS analysis of bloo

SUBMITTER: Arapidi G 

PROVIDER: S-EPMC5996950 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature