Early resting myocardial computed tomography perfusion for the detection of acute coronary syndrome in patients with coronary artery disease.

ABSTRACT:

Background

Acute rest single-photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) has high predictive value for acute coronary syndrome (ACS) in emergency department patients. Prior studies have shown excellent agreement between rest/stress computed tomography perfusion (CTP) and SPECT-MPI, but the value of resting CTP (rCTP) in acute chest pain triage remains unclear. We sought to determine the diagnostic accuracy of early rCTP, incremental value beyond obstructive coronary artery disease (CAD; ≥50% stenosis), and compared early rCTP to late stress SPECT-MPI in patients with CAD presenting with suspicion of ACS to the emergency department.

Methods and results

In this prespecified subanalysis of 183 patients (58.1±10.2 years; 33% women), we included p

SUBMITTER: Pursnani A 

PROVIDER: S-EPMC5996992 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature