Neonatal factors related to center variation in the incidence of late-onset circulatory collapse in extremely preterm infants.

ABSTRACT: BACKGROUND:Although late-onset circulatory collapse (LCC) is widely recognized in Japan, its etiology and the reason for center variation in its incidence remain unclear. This study's objectives were to identify the perinatal and neonatal factors related to LCC and to estimate the factors related to the center variation in the incidence of LCC. METHODS:Extremely preterm infants born between 2008 and 2012 who were registered in the database of the Neonatal Research Network, Japan were retrospectively analyzed. LCC was defined as a clinical diagnosis of LCC and the administration of steroids. We first identified the factors that were significantly related to LCC. We then examined the cause of the center variation in the incidence of LCC, using the standardized incidence ratios (SIRs) of LCC

SUBMITTER: Suzuki Y 

PROVIDER: S-EPMC5997318 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature